Exercise preconditioning-induced late phase of cardioprotection against exhaustive exercise: possible role of protein kinase C delta

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Exercise preconditioning-induced early and late phase of cardioprotection is associated with protein kinase C epsilon translocation.

BACKGROUND Exercise preconditioning (EP) can provide powerful protection to the heart. Evidence supports the contention that EP directly enhances myocardial tolerance to ischaemia through a protein kinase C (PKC)-mediated mechanism. However, studies investigating the role of isoform-specific PKC after EP are lacking. METHODS AND RESULTS In this study, a male Sprague-Dawley rat model of EP was...

متن کامل

The Role of Exercise Preconditioning in Cardioprotection against Ischemia Reperfusion Injury

Cardiovascular diseases are still the main cause of mortality around the world. Therefore, it is essential to develop practical means to reduce their burden. A wealth of evidence supports the role of physical exercise in attenuating many of the risk factors of cardiovascular diseases. Moreover, endurance training warrants protection against myocardial infarction. Exercise, even if performed ...

متن کامل

Cardioprotection Acquired Through Exercise: The Role of Ischemic Preconditioning

A great bulk of evidence supports the concept that regular exercise training can reduce the incidence of coronary events and increase survival chances after myocardial infarction. These exercise-induced beneficial effects on the myocardium are reached by means of the reduction of several risk factors relating to cardiovascular disease, such as high cholesterol, hypertension, obesity etc. Furthe...

متن کامل

Role of nitric-oxide synthase, free radicals, and protein kinase C delta in opioid-induced cardioprotection.

Opioids generate free radicals that mediate protection in isolated cultured cardiomyocytes. We hypothesize that the nature of these radicals is nitric oxide, and that nitric oxide activates the protein kinase C (PKC) delta isoform. Through this signal transduction pathway, opiates protect cardiomyocytes during hypoxia and reoxygenation. Cell viability was quantified in chick embryonic ventricul...

متن کامل

The Antioxidant Role of Artichoke (Cynara scolymus L.) Extract Against Exhaustive Exercise-Induced Oxidative Stress in Young Athletes

Background: Strenuous acute exercise induces oxidative stress in the active muscles and circulation, However, consumption of products rich in antioxidants may potentially ameliorate these effects. Objective: The present investigation was conducted to determine the effect of Artichoke (Cynara scolymus L.) extract on oxidative stress and antioxidant defense after aerobic exercise in young athle...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The Journal of Physiological Sciences

سال: 2014

ISSN: 1880-6546,1880-6562

DOI: 10.1007/s12576-014-0323-x